MIXED MESSAGE: Feds address vaccine regimen worries

Canada’s Intergovernmental Affairs Minister is sounding a note of hope that Canadians who mixed and matched vaccines will not have a problem crossing borders in the months ahead. Dominique LeBlanc says he expects that the current wariness of some foreign states – including the US – to mix and match vaccinations will “evolve.”

While Canadian health authorities say recipients of a Moderna dose should not hesitate to have Pfizer-BioNTech as their second jab – or vice versa – the US Food and Drug Administration has so far been reluctant to sanction the practice, saying it should only be done in “exceptional situations.”

The different view raises questions about how easily Canadians who mixed and matched will be able to cross into the United States once it opens its land borders to its northern neighbour.

Meanwhile many European countries do not recognize the AstraZeneca vaccine made at the Serum Institute of India, known by the brand name Covishield, meaning Canadians who received it could find themselves barred from entry.

Potential barriers to travellers go beyond border restrictions. Several cruise lines are refusing passengers who mixed and matched to any degree, including Norwegian Cruise Line.

Princess Cruise Lines, Holland America Line and Carnival Cruise Line say customers injected with a vector vaccine such as AstraZeneca followed by an mRNA vaccine such as Pfizer or Moderna are not considered fully vaccinated. However, a combination of Pfizer and Moderna will open the gangway to guests.

At a vritual virtual news conference Tuesday alongside Canada’s deputy chief public health officer, LeBlanc said data sharing and conversations between health bodies across the globe “will, we believe, over time lead to an evolution and an adjustment” of the more conservative approach of some countries’ regulatory bodies.

He added, “We don’t expect this to be a static circumstance. And I think over the next number of weeks and months there may be revisions provided by health authorities around the world with respect to these vaccine regimes.”

Dr. Howard Njoo pointed to studies on mix-and-max inoculation that suggest its effectiveness, saying that dropping case counts and death tolls in Canada reinforce the finding.

“That’s adding to the body of science,” he said. “The proof’s in the pudding. Hopefully, we can get to a place where we do make it easier for citizens of individual countries to be able to travel to other countries with a more common approach.”

Officials in Canada and a range of other countries – Germany, France, Italy, Spain and Sweden among them – have authorized people to follow one dose of AstraZeneca with a different vaccine.

Canada’s National Advisory Committee on Immunization changed its guidelines last month to allow Moderna or Pfizer to follow an initial dose of AstraZeneca.